1: Shaquille O'Neal

The athlete known as Shaq has been a superstar of basketball since he was drafted into the NBA in 1992. He's won four NBA championships and a host of other honors despite having arthritis in his big toe for several years. He blames his arthritis on years of running, jumping, and dunking with his 320-pound frame.

Medically Reviewed By: McDonough, Brian MD | Last Review Date: Mar 24, 2011

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