How Diabetes Affects Heart Disease Risk

Content provided by the Faculty of the Harvard Medical School

Diabetes raises the risk of heart disease by four to five times compared with people without the disease. For this reason, in addition to controlling blood sugar, people with diabetes need to pay close attention to controlling their blood pressure and cholesterol levels.

The treatment goals for people with diabetes are more stringent than those for people without diabetes. The good news is that lifestyle changes — and weight loss in particular—to improve your blood sugar usually will have a beneficial effect on the other values as well.

Blood pressure targets for people with diabetes

Your blood pressure reading has two parts, the systolic blood pressure (the first number) and the diastolic blood pressure (the second number). The systolic number represents the pressure while the heart is contracting and pushing blood into your vessels, and the diastolic number represents the pressure while the heart is refilling with blood between beats.


Related Video: Type 2 Wake-up Call

Close Panel

When the risk of blindness, emergency intervention, and serious nerve damage becomes a reality, most Type 2 diabetics hear a wake-up call and respond with action.

Medical Reviewer: Medical Reviewer: Gerald W. Smetana, MD Last Annual Review Date: Last Annual Review Date: August 30, 2010 © 2012 Healthgrades, Inc. All rights reserved. May not be reproduced or reprinted without permission from Healthgrades, Inc. Use of this information is governed by the Healthgrades User Agreement.

Indications and Usage for Lantus® (insulin glargine [rDNA origin] injection)

Prescription Lantus® is a long-acting insulin used to treat adults with type 2 diabetes and adults and children (6 years and older) with type 1 diabetes for the control of high blood sugar. It should be taken once a day at the same time each day to lower blood glucose.

Do not use Lantus® to treat diabetic ketoacidosis.

Important Safety Information for Lantus® (insulin glargine [rDNA origin] injection)

Do not take Lantus® if you are allergic to insulin or any of the inactive ingredients in Lantus®.

You must test your blood sugar levels while using insulin, such as Lantus®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Lantus® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Lantus® must only be used if the solution is clear and colorless with no particles visible. Do not share needles, insulin pens or syringes with others.

The most common side effect of insulin, including Lantus®, is low blood sugar (hypoglycemia), which may be serious. Some people may experience symptoms such as shaking, sweating, fast heartbeat, and blurred vision. Severe hypoglycemia may be serious and life threatening. It may cause harm to your heart or brain. Other possible side effects may include injection site reactions, including changes in fat tissue at the injection site, and allergic reactions, including itching and rash. In rare cases, some allergic reactions may be life threatening.

Tell your doctor about other medicines and supplements you are taking because they can change the way insulin works. Before starting Lantus®, tell your doctor about all your medical conditions including if you have liver or kidney problems, are pregnant or planning to become pregnant, or are breast-feeding or planning to breast-feed.

Lantus® SoloSTAR® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Please click here or the link below for the full prescribing information for Lantus®

US.GLA.12.05.107 © 2012 sanofi-aventis U.S. LLC, A SANOFI COMPANY


People with high blood pressure (known medically as hypertension) are more than twice as likely to suffer a heart attack or stroke as those with normal blood pressure. For that reason, people with diabetes are advised to keep their blood pressure as close to the ideal as possible, and always less than 130/80 millimeters of mercury (mm Hg).

Much of the dietary advice commonly recommended for people with diabetes—such as restricting salt intake, increasing physical activity, and losing weight—should help to lower your blood pressure. To make sure, your health care provider will test your blood pressure regularly. If diet and exercise alone do not bring your blood pressure into a healthy range, medications may be necessary to lower it.

The ABC’s of diabetes control

Having diabetes increases your risk for cardiovascular disease, including heart attack and stroke. If you have diabetes, you should pay close attention to factors that can put you at greater risk for heart trouble. These are often referred to as the “ABC’s:”

  • hemoglobin A1c (HbA1c) blood sugar test

  • Blood pressure

  • Cholesterol.

“ABC” Goals

HbA1c

Less than 7%

Blood pressure

Less than 130/80 mm Hg

LDL (bad) cholesterol

Less than 100 mg/dL

Triglycerides

Less than 150 mg/dL

HDL (good) cholesterol

More than 40 mg/dL in men and 50 mg/dL in women

Cholesterol levels

Your blood cholesterol level reflects the amount of one of the circulating lipids (fats) in your blood. This material travels in the bloodstream within spherical particles called lipoproteins. About two-thirds of blood cholesterol is in the form of low-density lipoprotein (LDL). This is sometimes referred to as “bad” cholesterol, because the higher the level of LDL cholesterol, the greater the risk for heart disease and stroke. High-density lipoprotein (HDL), on the other hand, counteracts the harmful effects of LDL. For that reason, HDL is sometimes referred to as “good” cholesterol. Another aspect of your lipid profile is the triglyceride level. Triglycerides are the main form of stored fat in the body and are carried by another type of lipoprotein. High triglyceride levels also increase the risk for heart disease, although not as much as LDL cholesterol.

Blood tests for cholesterol, which are measured after a fast of eight hours or more, provide information on total cholesterol as well as LDL, HDL, and triglyceride levels. These measurements provide another indicator of whether the changes you have made in your diet and activity levels and any medications you take have reduced your risk for heart disease, and whether you need to make any further adjustments.

Reference: Diabetes section on Better Medicine


This content is selected and managed by the Healthgrades editorial staff.

Diabetes Video Guide